Circulatory Enhancer Technology Overview
 
ResQPOD Impedance Threshold Device
 

Product Features

Technology

FAQs

Published Articles

Clinical Information

American Heart
Association Guidelines

Circulatory Enhancement Applications

Sudden Cardiac Arrest

Hypotension

Blood Loss

Instructions for Use

Product Literature
and Video
ResQGARD Impedance Threshold Device
 
 Home


Advanced Circulatory
Systems, Inc.
7615 Golden Triangle Drive,
Suite A
Eden Prairie, MN 55344
877-RESQPOD
1-877-737-7763
www.advancedcirculatory.com
 

 
  Published Articles*
 
  Click a Title to view the document
ResQPOD Clinical Studies
  Key Study Summaries
 

ResQPOD Key Study Summary
 
  Human Studies
  Tom Aufderheide, Medical Coll of Wisconsin, Milwaukee, WI, et al. A Tale of Seven EMS Systems: An Impedance Threshold Device and Improved CPR Techniques Double Survival Rates After Out-of-Hospital Cardiac Arrest. Circulation 2007; Supplement II;116(16);II-p36
 

Aufderheide TP, Pirrallo RG, et al. Clinical evaluation of an inspiratory impedance threshold device during standard cardiopulmonary resuscitation in patients with out-of-hospital cardiac arrest. Crit Care Med. 2005 Apr;33(4):734-40.
 

Pirrallo RG, Aufderheide TP, et al. Effect of an impedance threshold device on hemodynamics during conventional manual cardiopulmonary resuscitation. Resuscitation 2005; 66:13-20.
  Thayne RC, Thomas DC, et al. Use of an impedance threshold device improves short-term outcomes following out-of-hospital cardiac arrest. Resuscitation 2005; in press.
 

Wolcke BB, Mauer DK, et al. Comparison of standard CPR versus the combination of active compression-decompression cardiopulmonary resuscitation and an inspiratory impedance threshold device for out-of-hospital cardiac arrest. Circulation 2003;108(18):2201-5.
  Plaisance P, Lurie KG, Payen D. Inspiratory impedance during active compression-decompression CPR: a randomized evaluation in patients in cardiac arrest. Circulation 2000;101(9):989-94.
  Plaisance P, Lurie KG, et al. Evaluation of an impedance threshold device in patients receiving active compression-decompression cardiopulmonary resuscitation for out of hospital cardiac arrest. Resuscitation 2004;61(3):265-71.
  Plaisance P, Soleil C, et al. Use of an inspiratory impedance threshold device on a facemask and endotracheal tube to reduce intrathoracic pressures during the decompression phase of active compression decompression cardiopulmonary resuscitation. Crit Care Med 2005; 33(5):990-4.
 
  Animal Studies
  Bahlmann L, Klaus S, et al. Brain metabolism during CPR assessed with microdialysis. Resuscitation 2003;59(2):255-60.
  Lurie KG, Coffeen P, et al. Improving active compression-decompression CPR with an inspiratory impedance valve. Circulation 1995;91(6):1629-32.
 

Nadkarni V, Srinivasan V, et al. Rapid cerebral cooling during performance of active compression decompression resuscitation with an inspiratory impedance threshold device in a pig model of cardiac arrest. Circulation 2003;103(IV):379.
 

Raedler C, Voelckel WG, et al. Vasopressor response in a porcine model of hypothermic cardiac arrest is improved with active compression-decompression CPR using the inspiratory impedance threshold valve. Anesth Analg 2002;95(6):1496-502.
 

Voelckel WG, Lurie KG, et al. Effects of active compression-decompression CPR with the inspiratory threshold valve in a young porcine model of cardiac arrest. Pediatr Res 2002;51(4):523-7.
 

Voelckel WG, Lurie KG, et al. The effects of positive end-expiratory pressure during active compression decompression CPR with the inspiratory threshold valve. Anesth Analg 2001;92(4):967-74.
 

Lurie KG, Zielinski T, et al. Use of an inspiratory impedance valve improves neurologically intact survival in a porcine model of ventricular fibrillation. Circulation 2002;105(1):124-9.
 

Lurie KG, Mulligan KA, et al. Optimizing standard CPR with an inspiratory impedance threshold valve. Chest 1998;113(4):1084-90.
 

Lurie KG, Voelckel WG, et al. Improving standard CPR with an inspiratory impedance threshold valve in a porcine model of cardiac arrest. Anesth Analg 2001;93(3):649-55.
  Yannopoulos D, Sigurdsson G, et al. Reducing ventilation frequency combined with an inspiratory impedance device improves CPR efficiency in a swine model of cardiac arrest. Resuscitation 2004;(61):75-82.
  Langhelle A, Stromme T, et al. Inspiratory impedance threshold valve during CPR. Resuscitation 2002;52(1):39-48.
  Lurie KG, Ingbar D, et al. Potential role of the vocal cords during cardiopulmonary resuscitation. Circulation 1998;(SUPPL)98:17,I-478.
  Menegazzi JJ, Salcido DD, et al. Effects of an impedance threshold device on hemodynamics and restoration of spontaneous circulation in prolonged porcine ventricular fibrillation. Prehospital Emergency Care. 2007 Apr-Jun;11(2):179-85.

     ACSI Commentary
 
  Bench
  Lurie KG, Barnes TA, et al. Evaluation of a prototypic inspiratory impedance threshold valve designed to enhance the efficiency of CPR. Respiratory Care 2003;48(1):52-57
  Genzwuerker HV, Finteis T, et al. Influence of the impedance threshold valve (ITV) on ventilation with different airway devices. Abstract presented at ESA (Lisbon, Portugal; June 2004).
  Sugiyama A, Lurie KG, et al. Utilization of a model lung system to assess the effects of an inspiratory impedance threshold valve on the relationship between active decompression and intra-thoracic pressure. Resuscitation 1999;42(3):231-4.
 
  Review
  Lurie K, Zielinski T, et al. Improving the efficiency of CPR with an inspiratory impedance threshold valve. Crit Care Med. 2000;28(11 Suppl):N207-9.
  Sigurdsson G, Yannopoulos D, et al. Cardiorespiratory interactions and blood flow generation during cardiac arrest and other states of low blood flow. Curr Opin Crit Care 2003;9(3):183-8.
  Frascone RJ, Bitz D, Lurie K. Combination of active compression decompression cardiopulmonary resuscitation and the inspiratory impedance threshold device: state of the art. Curr Opin Crit Care 2004;10(3):193-201.
  Lurie KG, Zielinski T, et al. Augmentation of ventricular preload during treatment of cardiovascular collapse and cardiac arrest. Crit Care Med 2002;30(4):S162-5.
  Gabrielli A, Layon AJ, et al. Alternative ventilation strategies in CPR. Curr Opin Crit Care 2002;8(3):199-211.
  Babbs CF. Circulatory adjuncts. Newer methods of CPR. Cardiol Clin 2002;20(1):37-59.
  Lindner KH, Wenzel V. New mechanical methods for CPR. Literature study and analysis of effectiveness. Anaesthesist 1997;46(3):220-30.
  Lurie K. Mechanical devices for CPR: an update. Emerg Med Clin North Am 2002;20(4):771-84.
  Lurie KG. Recent advances in mechanical methods of CPR. Acta Anaesthesiol Scand Suppl. 1997;111:49-52.
  Lurie K. Bringing back the nearly dead. The hope and the challenge. Minn Med 2002;85(4):39-42.
  Lurie KG, Lindner KH. Recent advances in CPR. J Cardiovasc Electrophysiol 1997;8(5):584-600.
  Lurie K, Plaisance P, et al. Mechanical advances in CPR. Curr Opin Crit Care 2001;7(3):170-5.
  Lurie K, Sukhum P, et al. Recent advances in mechanical CPR devices. Curr Opin Crit Care. 1999;5:184-192.
  Lurie K, Voelckel W, et al. Use of an inspiratory impedance threshold valve during CPR: a progress report. Resuscitation 2000;44(3):219-30.
  Mauer D, Wolcke B, Dick W. Alternative methods of mechanical CPR. Resuscitation 2000;44(2):81-95.
  Sukhum P, Voelckel W, Lurie KG. Recent advances in active compression-decompression CPR. Baillière’s Clinical Anaesthesiology 2000;14(3)483-496.
  Wenzel V, Voelckel WG, et al. The new international guidelines for CPR: an analysis and comments on the most important changes. Anaesthesist 2001;50(5):342-57.
  Smith T. Alternative CPR devices. Curr Opin Crit Care 2002;8(3):219-23.
  Wigginton JG, Miller AH, et al. Mechanical devices for cardiopulmonary resuscitation. Curr Opin Crit Care 2005;11:in press.
 
  Quality of CPR
  Aufderheide TP, Sigurdsson G, et al. Hyperventilation induced hypotension during cardiopulmonary resuscitation. Circulation 2004;109(16):1960-1965.
  Aufderheide TP, Lurie KG. Death by hyperventilation: a common and life-threatening problem during cardiopulmonary resuscitation. Crit Care Med 2004;32(9):S345-S351.
  Aufderheide TP, Frascone RJ. Resuscitation in 2005: A primer focused on CPR for the professional rescuer. Submitted to EMS Magazine 2005.
  Aufderheide PT, Pirrallo RG, et al. Incomplete chest wall decompression: a clinical evaluation of CPR performance by EMS personnel and assessment of alternative manual chest compression–decompression techniques. Resuscitation 2005;64(3):353-362.
  Yannopoulos D, McKnite S, et al. Effects of incomplete chest wall decompression during cardiopulmonary resuscitation on coronary and cerebral perfusion pressures in a porcine model of cardiac arrest. Resuscitation 2005;64(3):363-372.

* Some of the studies on this website page have been conducted with the ResQPOD. The presentation of these studies is not intended to imply outcome-based claims not yet cleared by the US Food and Drug Administration (“FDA”). These studies have been conducted for the purpose of supporting the clearance of future outcomes-based claims by the FDA.
 ResQSystems
The generally cleared indication for the ResQPOD is a temporary increase in blood circulation during emergency care, hospital, clinic and home use. Click here to review the Instructions for Use. Studies are ongoing in the United States to evaluate the
long-term benefit of the ResQPOD for indications related to patients suffering from cardiac arrest, hypotension during dialysis
and severe blood loss.
 
For more information on completed clinical studies click here. The references on this website are not intended to imply specific outcome-based claims not yet cleared by the US Food and Drug Administration.

 All Rights Reserved. 2006